<?xml version="1.0" encoding="UTF-8"?><rss xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:content="http://purl.org/rss/1.0/modules/content/" xmlns:atom="http://www.w3.org/2005/Atom" version="2.0"><channel><title><![CDATA[liberen]]></title><description><![CDATA[transientanchors]]></description><link>https://www.liberendacayisaba.com/blog</link><generator>RSS for Node</generator><lastBuildDate>Tue, 16 Jun 2026 10:12:13 GMT</lastBuildDate><atom:link href="https://www.liberendacayisaba.com/blog-feed.xml" rel="self" type="application/rss+xml"/><item><title><![CDATA[Novel Myeloma Biomarkers from Single-cell Proteomics]]></title><description><![CDATA[Single-cell proteomics | Liquid biopsy Published in Nature Precision Oncology Multiple myeloma (MM) is accompanied by alterations to the normal plasma cell (PC) proteome, leading to changes to the tumor microenvironment and disease progression. There is a great need for understanding the consequences that lead to MM progression and for the discovery of new biomarkers that can aid clinical diagnostics and serve as targets for therapeutics. This study demonstrates the applicability of utilizing...]]></description><link>https://www.liberendacayisaba.com/post/novel-myeloma-biomarkers-from-single-cell-proteomics</link><guid isPermaLink="false">68c1f5e829ab8110bd6562d6</guid><pubDate>Mon, 18 Sep 2023 22:05:41 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/78c848_0970d0eedfed46c0b360426861ed6898~mv2.png/v1/fit/w_1000,h_1000,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator></dc:creator></item><item><title><![CDATA[Deep learning for Multimodal Data Integration]]></title><description><![CDATA[Machine learning | Multimodality | Precision oncology Book chapter in Circulating Tumor Cells, 2nd Edition Abstract The complex multimodality in clinical and liquid biopsy data generated by multiparametric diagnostic and tumor profiling technologies presents an exciting opportunity for developing innovative predictive mathematical models by harnessing large datasets across studies and institutional data repositories. Further, comprehensive liquid biopsy analysis with single-cell profiling...]]></description><link>https://www.liberendacayisaba.com/post/deep-learning-for-multimodal-data-integration</link><guid isPermaLink="false">68c1f6b56a8623255827c2db</guid><pubDate>Wed, 02 Aug 2023 22:09:22 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/78c848_ef8f857d1e2f481fb15b9e50eb78d01e~mv2.png/v1/fit/w_1000,h_1000,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator></dc:creator></item><item><title><![CDATA[Clonotypic and Transcriptomic Evolution of Myeloma]]></title><description><![CDATA[Single Cell Multiomics | Precursor Disease Published in Cancer Cell Abstract Multiple myeloma remains an incurable disease, and the cellular and molecular evolution from precursor conditions, including monoclonal gammopathy of undetermined significance and smoldering multiple myeloma, is incompletely understood. Here, we combine single-cell RNA and B cell receptor sequencing from fifty-two patients with myeloma precursors in comparison with myeloma and normal donors. Our comprehensive...]]></description><link>https://www.liberendacayisaba.com/post/clonotypic-and-transcriptomic-evolution-of-myeloma</link><guid isPermaLink="false">68c1f768f22b0a6988997eeb</guid><pubDate>Thu, 01 Jun 2023 22:13:57 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/78c848_fde116f8a5cd4b01a80e831b6125ae3c~mv2.jpg/v1/fit/w_1000,h_1000,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator></dc:creator></item><item><title><![CDATA[BCMA Expression in Circulating Cancer Cells.]]></title><description><![CDATA[Published in Int J Mol Sci. B-cell maturation antigen | Neoplastic progression Abstract B-cell maturation antigen (BCMA), a key regulator of B-cell proliferation and survival, is highly expressed in almost all cases of plasma cell neoplasms and B-lymphoproliferative malignancies. BCMA is a robust biomarker of plasma cells and a therapeutic target with substantial clinical significance. However, the expression of BCMA in circulating tumor cells of patients with hematological malignancies has...]]></description><link>https://www.liberendacayisaba.com/post/bcma-expression-in-circulating-cancer-cells</link><guid isPermaLink="false">68c1f8396a8623255827c6c7</guid><pubDate>Thu, 03 Nov 2022 22:15:36 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/78c848_afbe1315ce19478eaa06961f78b27349~mv2.png/v1/fit/w_1000,h_1000,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator></dc:creator></item><item><title><![CDATA[Morphogenomic Assay for Detecting Circulating Plasma Cells.]]></title><description><![CDATA[Published in Current Oncology Morphogenomics | Circulating myeloma cells Abstract Multiple myeloma is an incurable malignancy that initiates from a bone marrow resident clonal plasma cell and acquires successive mutational changes and genomic alterations, eventually resulting in tumor burden accumulation and end-organ damage. It has been recently recognized that myeloma secondary genomic events result in extensive sub-clonal heterogeneity both in localized bone marrow areas and circulating...]]></description><link>https://www.liberendacayisaba.com/post/morphogenomic-assay-for-detecting-circulating-plasma-cells</link><guid isPermaLink="false">68c1f897f22b0a69889982e3</guid><pubDate>Thu, 21 Apr 2022 22:17:29 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/78c848_61aaeede043245ac905b9be38372b7c4~mv2.png/v1/fit/w_1000,h_1000,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator></dc:creator></item><item><title><![CDATA[Machine Learning Models to Predict off-target Effects in RNAi.]]></title><description><![CDATA[RNA interference | Machine Learning Abstract RNA interference (RNAi) has proved to be a valuable pathway process and successful tool for posttranscriptional gene regulation in prokaryotic and invertebrate systems. With high specificity, small interfering RNAs (siRNAs) induce mRNA degradation and thus inhibiting gene expression. This mechanism enables the design of synthetic siRNAs for use in mammalian cell loss-of-function experiments, drug target identification, and as a potentially viable...]]></description><link>https://www.liberendacayisaba.com/post/machine-learning-models-to-predict-off-target-effects-in-rnai</link><guid isPermaLink="false">68c1f94eeb19dd158fa4dd80</guid><pubDate>Mon, 10 Aug 2015 22:19:39 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/78c848_4dce8b7f21d74dfd9767fe1a39fbf734~mv2.png/v1/fit/w_1000,h_1000,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator>liberendacayisaba</dc:creator></item><item><title><![CDATA[Homology Modeling and Inhibitors of hSGLTs.]]></title><description><![CDATA[Na/Glu Co-transporters | Molecular Docking Abstract The sodium-dependent glucose co-transporters (SGLTs) are membrane proteins that function by harnessing the energy stored in transmembrane sodium gradients to actively transport sugars, which are crucial for maintaining cellular energy homeostasis. In humans, dietary glucose is imported via SGLT1 (hSGLT1) in the small intestines, while hSGLT2 reabsorbs filtered glucose in the kidneys. Diabetic patients suffer from improper sugar handling that...]]></description><link>https://www.liberendacayisaba.com/post/homology-modeling-and-inhibitors-of-hsglts</link><guid isPermaLink="false">68c1f99e6a8623255827cbc1</guid><pubDate>Fri, 01 Aug 2014 22:20:56 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/78c848_85b7c29ca0d04ecda9f8215ca2308f66~mv2.png/v1/fit/w_1000,h_1000,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator>liberendacayisaba</dc:creator></item><item><title><![CDATA[Molecular Taxonomy of Mirids.]]></title><description><![CDATA[Molecular Biology | Bioinformatics Background While humans are equipped with the intelligence to make sophisticated machines and travel into space, insects really rule the world. With an estimated 10 million species and more biomass than humans, insects are the most successful creatures on Earth. While the reason for their success remains an important subject of scientific research, there is still an enormous gap in our understanding of insect taxonomy (the identification and description of...]]></description><link>https://www.liberendacayisaba.com/post/molecular-taxonomy-of-mirids</link><guid isPermaLink="false">68c1f9ec6a8623255827cc97</guid><pubDate>Tue, 10 Jul 2012 22:23:21 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/78c848_74b1e2e61f804687a349706af3ce1956~mv2.png/v1/fit/w_1000,h_1000,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator>liberendacayisaba</dc:creator></item></channel></rss>